ColE1-Plasmid Production in Escherichia coli: Mathematical Simulation and Experimental Validation

Plasmids have become very important as pharmaceutical gene vectors in the fields of gene therapy and genetic vaccination in the past years. In this study, we present a dynamic model to simulate the ColE1-like plasmid replication control, once for a DH5α-strain carrying a low copy plasmid (DH5α-pSUP...

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Detalles Bibliográficos
Autores principales: Freudenau, Inga, Lutter, Petra, Baier, Ruth, Schleef, Martin, Bednarz, Hanna, Lara, Alvaro R., Niehaus, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555960/
https://www.ncbi.nlm.nih.gov/pubmed/26389114
http://dx.doi.org/10.3389/fbioe.2015.00127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555960/
https://www.ncbi.nlm.nih.gov/pubmed/26389114
http://dx.doi.org/10.3389/fbioe.2015.00127

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