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ColE1-Plasmid Production in Escherichia coli: Mathematical Simulation and Experimental Validation
Plasmids have become very important as pharmaceutical gene vectors in the fields of gene therapy and genetic vaccination in the past years. In this study, we present a dynamic model to simulate the ColE1-like plasmid replication control, once for a DH5α-strain carrying a low copy plasmid (DH5α-pSUP...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555960/ https://www.ncbi.nlm.nih.gov/pubmed/26389114 http://dx.doi.org/10.3389/fbioe.2015.00127 |