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Genetic polymorphisms of PAI-1 and PAR-1 are associated with acute normal tissue toxicity in Chinese rectal cancer patients treated with pelvic radiotherapy

Plasminogen activator inhibitor type 1 (PAI-1) and protease-activated receptor-1 (PAR-1) are crucial mediators of the intestinal microenvironment and are involved in radiation-induced acute and chronic injury. To evaluate whether genetic polymorphisms of PAI-1 and PAR-1 were predictors of radiation-...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Wang, Mengyun, Shi, Tingyan, Shen, Lijun, Zhu, Ji, Sun, Menghong, Deng, Yun, Liang, Liping, Li, Guichao, Wu, Yongxin, Fan, Ming, Wei, Qingyi, Zhang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556037/
https://www.ncbi.nlm.nih.gov/pubmed/26347502
http://dx.doi.org/10.2147/OTT.S83723