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Frequency Modulated Translocational Oscillations of Nrf2 Mediate the Antioxidant Response Element Cytoprotective Transcriptional Response

Aims: Stress responsive signaling coordinated by nuclear factor erythroid 2-related factor 2 (Nrf2) provides an adaptive response for protection of cells against toxic insults, oxidative stress and metabolic dysfunction. Nrf2 regulates a battery of protective genes by binding to regulatory antioxida...

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Detalles Bibliográficos
Autores principales: Xue, Mingzhan, Momiji, Hiroshi, Rabbani, Naila, Barker, Guy, Bretschneider, Till, Shmygol, Anatoly, Rand, David A., Thornalley, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556091/
https://www.ncbi.nlm.nih.gov/pubmed/25178584
http://dx.doi.org/10.1089/ars.2014.5962