Inhibition of hypoxia inducible factor-1α downregulates the expression of epithelial to mesenchymal transition early marker proteins without undermining cell survival in hypoxic lens epithelial cells

PURPOSE: The purpose of this study was to identify potential therapeutic strategies to slow down or prevent the expression of early-onset epithelial to mesenchymal transition (EMT) marker proteins (fibronectin and alpha smooth muscle actin, α-SMA) without sacrificing the synthesis and accumulation o...

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Detalles Bibliográficos
Autores principales: Cammarata, Patrick R., Neelam, Sudha, Brooks, Morgan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556159/
https://www.ncbi.nlm.nih.gov/pubmed/26392741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556159/
https://www.ncbi.nlm.nih.gov/pubmed/26392741

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