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A Dunnione Compound MB12662 Improves Cisplatin-Induced Tissue Injury and Emesis

The present study was aimed to investigate the effects of MB12662, a synthetic dunnione compound, on cisplatin-induced vomiting reflexes and intestinal, renal, immune system, and hematopoietic toxicities in ferrets and mice, respectively. Male ICR mice were orally administered MB12662 (5, 10, 25 or...

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Detalles Bibliográficos
Autores principales: Park, Dongsun, Jo, In Geun, Jang, Ja Young, Kwak, Tae Hwan, Yoo, Sang Ku, Jeon, Jeong Hee, Choi, Ehn-Kyoung, Joo, Seong Soo, Kim, Okjin, Kim, Yun-Bae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556205/
https://www.ncbi.nlm.nih.gov/pubmed/26336585
http://dx.doi.org/10.4062/biomolther.2015.034