Targeting Highly Structured RNA by Cooperative Action of siRNAs and Helper Antisense Oligomers in Living Cells

RNA target accessibility is one of the most important factors limiting the efficiency of RNA interference-mediated RNA degradation. However, targeting RNA viruses in their poorly accessible, highly structured regions can be advantageous because these regions are often conserved in sequence and thus...

Descripción completa

Detalles Bibliográficos
Autores principales: Dutkiewicz, Mariola, Ojdowska, Agata, Kuczynski, Jakub, Lindig, Vanessa, Zeichhardt, Heinz, Kurreck, Jens, Ciesiołka, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556297/
https://www.ncbi.nlm.nih.gov/pubmed/26308932
http://dx.doi.org/10.1371/journal.pone.0136395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556297/
https://www.ncbi.nlm.nih.gov/pubmed/26308932
http://dx.doi.org/10.1371/journal.pone.0136395

Ejemplares similares