Cyclodextrin Alters GABAergic Input to CA1 Pyramidal Cells in Wild-Type But Not in NPC1-Deficient Mice

Niemann–Pick type C1 disease (NPC1) is a neurodegenerative disorder caused by mutations in the NPC1 gene. Actual, no causative treatment for NPC1 is available, although some drugs have been proven to be beneficial to patients, for example, 2-hydroxypropyl-β-cyclodextrin (CDX). In this study, we used...

Descripción completa

Detalles Bibliográficos
Autores principales: Frech, Moritz J., Rabenstein, Michael, Bovensiepen, Katja, Rost, Sebastian, Rolfs, Arndt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556338/
https://www.ncbi.nlm.nih.gov/pubmed/26392920
http://dx.doi.org/10.1089/biores.2015.0023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556338/
https://www.ncbi.nlm.nih.gov/pubmed/26392920
http://dx.doi.org/10.1089/biores.2015.0023

Ejemplares similares