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Cyclodextrin Alters GABAergic Input to CA1 Pyramidal Cells in Wild-Type But Not in NPC1-Deficient Mice
Niemann–Pick type C1 disease (NPC1) is a neurodegenerative disorder caused by mutations in the NPC1 gene. Actual, no causative treatment for NPC1 is available, although some drugs have been proven to be beneficial to patients, for example, 2-hydroxypropyl-β-cyclodextrin (CDX). In this study, we used...
Autores principales: | Frech, Moritz J., Rabenstein, Michael, Bovensiepen, Katja, Rost, Sebastian, Rolfs, Arndt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556338/ https://www.ncbi.nlm.nih.gov/pubmed/26392920 http://dx.doi.org/10.1089/biores.2015.0023 |
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