Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease

Methionine metabolism plays a central role in methylation reactions, production of glutathione and methylarginines, and modulating homocysteine levels. The mechanisms by which these are affected in NAFLD are not fully understood. The aim is to perform a metabolomic, molecular and epigenetic analyses...

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Detalles Bibliográficos
Autores principales: Pacana, Tommy, Cazanave, Sophie, Verdianelli, Aurora, Patel, Vaishali, Min, Hae-Ki, Mirshahi, Faridoddin, Quinlivan, Eoin, Sanyal, Arun J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556375/
https://www.ncbi.nlm.nih.gov/pubmed/26322888
http://dx.doi.org/10.1371/journal.pone.0136822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556375/
https://www.ncbi.nlm.nih.gov/pubmed/26322888
http://dx.doi.org/10.1371/journal.pone.0136822

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