53BP1 suppresses epithelial–mesenchymal transition by downregulating ZEB1 through microRNA-200b/429 in breast cancer

Epithelial–mesenchymal transition (EMT) is an important mechanism of cancer invasion and metastasis. Although p53 binding protein 1 (53BP1) has been implicated in several biological processes, its function in EMT of human cancers has not yet been reported. Here, we show that 53BP1 negatively regulat...

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Detalles Bibliográficos
Autores principales: Kong, Xiangnan, Ding, Xia, Li, Xiaoyan, Gao, Sumei, Yang, Qifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556386/
https://www.ncbi.nlm.nih.gov/pubmed/26011542
http://dx.doi.org/10.1111/cas.12699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556386/
https://www.ncbi.nlm.nih.gov/pubmed/26011542
http://dx.doi.org/10.1111/cas.12699

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