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Src/STAT3-dependent heme oxygenase-1 induction mediates chemoresistance of breast cancer cells to doxorubicin by promoting autophagy

Chemotherapeutic resistance in breast cancer, whether acquired or intrinsic, remains a major clinical obstacle. Thus, increasing tumor cell sensitivity to chemotherapeutic agents will be helpful in improving the clinical management of breast cancer. In the present study, we found an induction of HO-...

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Detalles Bibliográficos
Autores principales: Tan, Qixing, Wang, Hongli, Hu, Yongliang, Hu, Meiru, Li, Xiaoguang,  , Aodengqimuge, Ma, Yuanfang, Wei, Changyuan, Song, Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556392/
https://www.ncbi.nlm.nih.gov/pubmed/26041409
http://dx.doi.org/10.1111/cas.12712