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CRKL oncogene is downregulated by p53 through miR-200s

Tumor suppressive miRNAs that target oncogenes are frequently downregulated in cancers, and this downregulation leads to oncogene pathway activation. Thus, tumor suppressive miRNAs and their target oncogenes have been proposed as useful targets in cancer treatment. miR-200 family downregulation has...

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Detalles Bibliográficos
Autores principales: Tamura, Miyuki, Sasaki, Yasushi, Kobashi, Kenta, Takeda, Kousuke, Nakagaki, Takafumi, Idogawa, Masashi, Tokino, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556393/
https://www.ncbi.nlm.nih.gov/pubmed/26079153
http://dx.doi.org/10.1111/cas.12713