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Low Expression of Mfn2 Is Associated with Mitochondrial Damage and Apoptosis of Ovarian Tissues in the Premature Ovarian Failure Model

BACKGROUND: This study aimed to construct a working model for detecting the mitochondrial damage and expression of Mfn2. It furthermore explored the pathogenesis of premature ovarian failure (POF) induced by cisplatin. METHOD: Forty young female mice were divided randomly into two groups. The first...

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Detalles Bibliográficos
Autores principales: Chen, Wenqi, Xu, Xiaoyan, Wang, Lingjuan, Bai, Ge, Xiang, Wenpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556514/
https://www.ncbi.nlm.nih.gov/pubmed/26327438
http://dx.doi.org/10.1371/journal.pone.0136421