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IgM exacerbates glomerular disease progression in complement induced glomerulopathy

While glomerular IgM deposition occurs in a variety of glomerular diseases the mechanism of deposition and its clinical significance remain controversial. Some have theorized IgM becomes passively trapped in areas of glomerulosclerosis. However, recent studies found that IgM specifically binds damag...

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Detalles Bibliográficos
Autores principales: Panzer, Sarah E., Laskowski, Jennifer, Renner, Brandon, Kulik, Liudmila, Ljubanovic, Danica, Huber, Kendra M., Zhong, Weixiong, Pickering, Matthew C., Holers, V. Michael, Thurman, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556608/
https://www.ncbi.nlm.nih.gov/pubmed/25945405
http://dx.doi.org/10.1038/ki.2015.120