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The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine

The disease caused by Plasmodium falciparum (Pf) involves different clinical manifestations that, cumulatively, kill hundreds of thousands every year. Placental malaria (PM) is one such manifestation in which Pf infected erythrocytes (IE) bind to chondroitin sulphate A (CSA) through expression of VA...

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Detalles Bibliográficos
Autores principales: Nielsen, Morten A., Resende, Mafalda, de Jongh, Willem A., Ditlev, Sisse B., Mordmüller, Benjamin, Houard, Sophie, Ndam, Nicaise Tuikue, Agerbæk, Mette Ø., Hamborg, Mette, Massougbodji, Achille, Issifou, Saddou, Strøbæk, Anette, Poulsen, Lars, Leroy, Odile, Kremsner, Peter G., Chippaux, Jean-Philippe, Luty, Adrian J. F., Deloron, Philippe, Theander, Thor G., Dyring, Charlotte, Salanti, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556615/
https://www.ncbi.nlm.nih.gov/pubmed/26327283
http://dx.doi.org/10.1371/journal.pone.0135406