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The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine
The disease caused by Plasmodium falciparum (Pf) involves different clinical manifestations that, cumulatively, kill hundreds of thousands every year. Placental malaria (PM) is one such manifestation in which Pf infected erythrocytes (IE) bind to chondroitin sulphate A (CSA) through expression of VA...
Autores principales: | Nielsen, Morten A., Resende, Mafalda, de Jongh, Willem A., Ditlev, Sisse B., Mordmüller, Benjamin, Houard, Sophie, Ndam, Nicaise Tuikue, Agerbæk, Mette Ø., Hamborg, Mette, Massougbodji, Achille, Issifou, Saddou, Strøbæk, Anette, Poulsen, Lars, Leroy, Odile, Kremsner, Peter G., Chippaux, Jean-Philippe, Luty, Adrian J. F., Deloron, Philippe, Theander, Thor G., Dyring, Charlotte, Salanti, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556615/ https://www.ncbi.nlm.nih.gov/pubmed/26327283 http://dx.doi.org/10.1371/journal.pone.0135406 |
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