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Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints

Dengue viruses (DENV) cause debilitating and potentially life-threatening acute disease throughout the tropical world. While drug development efforts are underway, there are concerns that resistant strains will emerge rapidly. Indeed, antiviral drugs that target even conserved regions in other RNA v...

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Detalles Bibliográficos
Autores principales: Sessions, October M., Wilm, Andreas, Kamaraj, Uma Sangumathi, Choy, Milly M., Chow, Angelia, Chong, Yuwen, Ong, Xin Mei, Nagarajan, Niranjan, Cook, Alex R., Ooi, Eng Eong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556638/
https://www.ncbi.nlm.nih.gov/pubmed/26327586
http://dx.doi.org/10.1371/journal.pntd.0004044