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Folliculogenesis Is Not Fully Inhibited during GnRH Analogues Treatment in Mice Challenging Their Efficiency to Preserve the Ovarian Reserve during Chemotherapy in This Model

As many chemotherapy regimens induce follicular depletion, fertility preservation became a major concern in young cancer patients. By maintaining follicles at the resting stage, gonadotropin-releasing hormone analogues (GnRHa) were proposed as an ovarian-protective option during chemotherapy. Howeve...

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Detalles Bibliográficos
Autores principales: Horicks, Florence, Van Den Steen, Géraldine, Houben, Sarah, Englert, Yvon, Demeestere, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556658/
https://www.ncbi.nlm.nih.gov/pubmed/26325271
http://dx.doi.org/10.1371/journal.pone.0137164