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Folliculogenesis Is Not Fully Inhibited during GnRH Analogues Treatment in Mice Challenging Their Efficiency to Preserve the Ovarian Reserve during Chemotherapy in This Model
As many chemotherapy regimens induce follicular depletion, fertility preservation became a major concern in young cancer patients. By maintaining follicles at the resting stage, gonadotropin-releasing hormone analogues (GnRHa) were proposed as an ovarian-protective option during chemotherapy. Howeve...
Autores principales: | Horicks, Florence, Van Den Steen, Géraldine, Houben, Sarah, Englert, Yvon, Demeestere, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556658/ https://www.ncbi.nlm.nih.gov/pubmed/26325271 http://dx.doi.org/10.1371/journal.pone.0137164 |
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