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An Integrated Framework Advancing Membrane Protein Modeling and Design

Membrane proteins are critical functional molecules in the human body, constituting more than 30% of open reading frames in the human genome. Unfortunately, a myriad of difficulties in overexpression and reconstitution into membrane mimetics severely limit our ability to determine their structures....

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Detalles Bibliográficos
Autores principales: Alford, Rebecca F., Koehler Leman, Julia, Weitzner, Brian D., Duran, Amanda M., Tilley, Drew C., Elazar, Assaf, Gray, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556676/
https://www.ncbi.nlm.nih.gov/pubmed/26325167
http://dx.doi.org/10.1371/journal.pcbi.1004398