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Prion Protein Protects against Renal Ischemia/Reperfusion Injury

The cellular prion protein (PrP(C)), a protein most noted for its link to prion diseases, has been found to play a protective role in ischemic brain injury. To investigate the role of PrP(C) in the kidney, an organ highly prone to ischemia/reperfusion (IR) injury, we examined wild-type (WT) and PrP(...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Cowden, Daniel, Zhang, Fan, Yuan, Jue, Siedlak, Sandra, Abouelsaad, Mai, Zeng, Liang, Zhou, Xuefeng, O'Toole, John, Das, Alvin S., Kofskey, Diane, Warren, Miriam, Bian, Zehua, Cui, Yuqi, Tan, Tao, Kresak, Adam, Wyza, Robert E., Petersen, Robert B., Wang, Gong-Xian, Kong, Qingzhong, Wang, Xinglong, Sedor, John, Zhu, Xiongwei, Zhu, Hua, Zou, Wen-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556704/
https://www.ncbi.nlm.nih.gov/pubmed/26327228
http://dx.doi.org/10.1371/journal.pone.0136923