Failure of Neuroprotection Despite Microglial Suppression by Delayed-Start Myeloperoxidase Inhibition in a Model of Advanced Multiple System Atrophy: Clinical Implications

Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disease. Post-mortem hallmarks of MSA neuropathology include oligodendroglial α-synuclein (αSYN) inclusions, striatonigral degeneration, olivopontocerebellar atrophy, and increased microglial activation that accompanies the wid...

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Detalles Bibliográficos
Autores principales: Kaindlstorfer, Christine, Sommer, Patrick, Georgievska, Biljana, Mather, Robert J., Kugler, Alan R., Poewe, Werner, Wenning, Gregor K., Stefanova, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556742/
https://www.ncbi.nlm.nih.gov/pubmed/26194617
http://dx.doi.org/10.1007/s12640-015-9547-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556742/
https://www.ncbi.nlm.nih.gov/pubmed/26194617
http://dx.doi.org/10.1007/s12640-015-9547-7

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