NOSH-sulindac (AVT-18A) is a novel nitric oxide- and hydrogen sulfide-releasing hybrid that is gastrointestinal safe and has potent anti-inflammatory, analgesic, antipyretic, anti-platelet, and anti-cancer properties

Sulindac is chemopreventive and has utility in patients with familial adenomatous polyposis; however, side effects preclude its long-term use. NOSH-sulindac (AVT-18A) releases nitric oxide and hydrogen sulfide, was designed to be a safer alternative. Here we compare the gastrointestinal safety, anti...

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Detalles Bibliográficos
Autores principales: Kashfi, Khosrow, Chattopadhyay, Mitali, Kodela, Ravinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556776/
https://www.ncbi.nlm.nih.gov/pubmed/26298203
http://dx.doi.org/10.1016/j.redox.2015.08.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556776/
https://www.ncbi.nlm.nih.gov/pubmed/26298203
http://dx.doi.org/10.1016/j.redox.2015.08.012

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