Cargando…

NOSH-sulindac (AVT-18A) is a novel nitric oxide- and hydrogen sulfide-releasing hybrid that is gastrointestinal safe and has potent anti-inflammatory, analgesic, antipyretic, anti-platelet, and anti-cancer properties

Sulindac is chemopreventive and has utility in patients with familial adenomatous polyposis; however, side effects preclude its long-term use. NOSH-sulindac (AVT-18A) releases nitric oxide and hydrogen sulfide, was designed to be a safer alternative. Here we compare the gastrointestinal safety, anti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kashfi, Khosrow, Chattopadhyay, Mitali, Kodela, Ravinder
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556776/ https://www.ncbi.nlm.nih.gov/pubmed/26298203 http://dx.doi.org/10.1016/j.redox.2015.08.012

Ejemplares similares

Gastrointestinal safety, chemotherapeutic potential, and classic pharmacological profile of NOSH‐naproxen (AVT‐219) a dual NO‐ and H(2)S‐releasing hybrid
por: Chattopadhyay, Mitali, et al.
Publicado: (2016)

Positional isomerism markedly affects the growth inhibition of colon cancer cells by NOSH-aspirin: COX inhibition and modeling()
por: Vannini, Federica, et al.
Publicado: (2015)

NOSH-aspirin (NBS-1120), a dual nitric oxide and hydrogen sulfide-releasing hybrid, reduces inflammatory pain
por: Fonseca, Miriam D, et al.
Publicado: (2015)

Hydrogen sulfide-releasing naproxen suppresses colon cancer cell growth and inhibits NF-κB signaling
por: Kodela, Ravinder, et al.
Publicado: (2015)

Nitric Oxide-Releasing Aspirin Suppresses NF-κB Signaling in Estrogen Receptor Negative Breast Cancer Cells in Vitro and in Vivo
por: Nath, Niharika, et al.
Publicado: (2015)

Exploring the Potential of Nitric Oxide and Hydrogen Sulfide (NOSH)-Releasing Synthetic Compounds as Novel Priming Agents against Drought Stress in Medicago sativa Plants
por: Antoniou, Chrystalla, et al.
Publicado: (2020)

Anticancer and Anti-Inflammatory Mechanisms of NOSH-Aspirin and Its Biological Effects
por: Zhou, Jun, et al.
Publicado: (2022)

Antipyretic, analgesic and anti-inflammatory activity of Viola betonicifolia whole plant
por: Muhammad, Naveed, et al.
Publicado: (2012)

Retracted: Anticancer and Anti-Inflammatory Mechanisms of NOSH-Aspirin and Its Biological Effects
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

ON THE ANTIPYRETIC, ANTI-INFLAMMATORY, ANALGESIC AND MOLLUSCICIDAL PROPERTIES OF POLYSCIAS FRUTICOSA (L) HARMS
por: Bernard, Bensita Mary, et al.
Publicado: (1998)

Antipyretic, analgesic and anti-oxidative activities of Aquilaria crassna leaves extract in rodents
por: Sattayasai, Jintana, et al.
Publicado: (2012)

Anti-Febrin as Antipyretic and Antiseptic
Publicado: (1887)

Evaluation of analgesic, antipyretic and anti-inflammatory activity on Cordia dichotoma G. Forst. Leaf
por: Gupta, Richa, et al.
Publicado: (2015)

Evaluation of antioxidant, anti-inflammatory, analgesic and antipyretic activities of the stem bark of Sapindus mukorossi
por: Shah, Madeha, et al.
Publicado: (2017)

Mechanistic assessment of the analgesic, anti-inflammatory and antipyretic actions of Dalbergia saxatilis in animal models
por: Yemitan, Omoniyi K., et al.
Publicado: (2017)

Anti-Inflammatory, Antipyretic, and Analgesic Properties of Potamogeton perfoliatus Extract: In Vitro and In Vivo Study
por: Rezq, Samar, et al.
Publicado: (2021)

Antipyretic, anti-inflammatory and analgesic activity of Acacia hydaspica R. Parker and its phytochemical analysis
por: Afsar, Tayyaba, et al.
Publicado: (2015)

Novel sulindac derivatives: synthesis, characterisation, evaluation of antioxidant, analgesic, anti-inflammatory, ulcerogenic and COX-2 inhibition activity
por: Bhat, Mashooq A., et al.
Publicado: (2020)

Anti-Inflammatory, Analgesic, and Antipyretic Activities of the Ethanol Extract of Piper interruptum Opiz. and Piper chaba Linn.
por: Sireeratawong, Seewaboon, et al.
Publicado: (2012)

An evaluation of the anti-inflammatory, antipyretic and analgesic effects of hydroethanol leaf extract of Albizia zygia in animal models
por: Abotsi, Wonder Kofi Mensah, et al.
Publicado: (2016)

Antihyperlipidemic, anti-inflammatory, analgesic, and antipyretic activities of “dimethyl dimethoxy biphenyl dicarboxylate” in male Wistar rats
por: Abdallah, Heba M. I., et al.
Publicado: (2022)

Gas chromatography-mass spectrometry profiling and analgesic, anti-inflammatory, antipyretic, and antihyperglycemic potentials of Persea americana
por: Mahmoud, Amany Hamouda, et al.
Publicado: (2021)

Evaluation of Toxicity, Bacteriostatic, Analgesic, Anti-Inflammatory, and Antipyretic Activities of Huangqin-Honghua-Pugongying-Jinyinhua Extract
por: Ye, Dongyang, et al.
Publicado: (2021)

Analgesic, Anti-inflammatory, Antipyretic, and In Silico Measurements of Sonneratia caseolaris (L.) Fruits from Sundarbans, Bangladesh
por: Kundu, Pritam, et al.
Publicado: (2022)

NOSH-NBP, a Novel Nitric Oxide and Hydrogen Sulfide- Releasing Hybrid, Attenuates Ischemic Stroke-Induced Neuroinflammatory Injury by Modulating Microglia Polarization
por: Ji, Jing, et al.
Publicado: (2017)

The Renin–Angiotensin-Aldosterone System, Nitric Oxide, and Hydrogen Sulfide at the Crossroads of Hypertension and COVID-19: Racial Disparities and Outcomes
por: Ranjbar, Tara, et al.
Publicado: (2022)

AVT02: An Adalimumab Biosimilar
por: Kang, Connie
Publicado: (2022)

A Polyphenols-Rich Extract from Moricandia sinaica Boiss. Exhibits Analgesic, Anti-Inflammatory and Antipyretic Activities In Vivo
por: El-mekkawy, Sahar, et al.
Publicado: (2020)

Hydrogen Sulfide—a potent multichannel anti-arrhythmic drug
por: Zhong, Guang-Zhen
Publicado: (2010)

Experimental evaluation of antipyretic and analgesic activities of aspartame
por: Tandel, Kirtida R.
Publicado: (2011)

Experimental evaluation of antipyretic and analgesic activity of aspartame
por: Pradhan, Sapna, et al.
Publicado: (2011)

Antiinflammatory, Analgesic and Antipyretic Activity of Certain Thiazolidinones
por: Taranalli, A. D., et al.
Publicado: (2008)

Social effects on AVT and CRF systems
por: Backström, Tobias, et al.
Publicado: (2021)

Correction to: AVT02: An Adalimumab Biosimilar
por: Kang, Connie
Publicado: (2022)

Evaluation of anti-inflammatory, analgesic, and antipyretic activities of the ethanol extract from Murdannia loriformis (Hassk.) Rolla Rao et Kammathy
por: Kunnaja, Phraepakaporn, et al.
Publicado: (2014)

Screening of anti-inflammatory and antipyretic activity of Vitex leucoxylon Linn
por: Shukla, Padmini, et al.
Publicado: (2010)

Radioprotective Potential of Sulindac Sulfide to Prevent DNA Damage Due to Ionizing Radiation
por: Torabizadeh, Seyedeh Atekeh, et al.
Publicado: (2019)

Antiinflammatory, Analgesic and Antipyretic Activities of Mimusops elengi Linn
por: Purnima, A., et al.
Publicado: (2010)

Analgesic and antipyretic activities of Momordica charantia Linn. fruits
por: Patel, Roshan, et al.
Publicado: (2010)

Caffeine Intoxication Due to Antipyretic Analgesic Overdose in an Adolescent
por: Horikawa, Yohei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_enlgrl59qpbpd2i5qainhcckkc