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In vivo parameters influencing 2-Cys Prx oligomerization: The role of enzyme sulfinylation

2-Cys Prxs are H(2)O(2)-specific antioxidants that become inactivated by enzyme hyperoxidation at elevated H(2)O(2) levels. Although hyperoxidation restricts the antioxidant physiological role of these enzymes, it also allows the enzyme to become an efficient chaperone holdase. The critical molecula...

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Detalles Bibliográficos
Autores principales: Noichri, Y., Palais, G., Ruby, V., D’Autreaux, B., Delaunay-Moisan, A., Nyström, T., Molin, M., Toledano, M.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556779/
https://www.ncbi.nlm.nih.gov/pubmed/26335398
http://dx.doi.org/10.1016/j.redox.2015.08.011