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In vivo parameters influencing 2-Cys Prx oligomerization: The role of enzyme sulfinylation
2-Cys Prxs are H(2)O(2)-specific antioxidants that become inactivated by enzyme hyperoxidation at elevated H(2)O(2) levels. Although hyperoxidation restricts the antioxidant physiological role of these enzymes, it also allows the enzyme to become an efficient chaperone holdase. The critical molecula...
Autores principales: | Noichri, Y., Palais, G., Ruby, V., D’Autreaux, B., Delaunay-Moisan, A., Nyström, T., Molin, M., Toledano, M.B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556779/ https://www.ncbi.nlm.nih.gov/pubmed/26335398 http://dx.doi.org/10.1016/j.redox.2015.08.011 |
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