BRCA1 185delAG Mutation Enhances Interleukin-1β Expression in Ovarian Surface Epithelial Cells

Familial history remains the strongest risk factor for developing ovarian cancer (OC) and is associated with germline BRCA1 mutations, such as the 185delAG founder mutation. We sought to determine whether normal human ovarian surface epithelial (OSE) cells expressing the BRCA1 185delAG mutant, BRAT,...

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Detalles Bibliográficos
Autores principales: Woolery, Kamisha T., Mohamed, Mai, Linger, Rebecca J., Dobrinski, Kimberly P., Roman, Jesse, Kruk, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556869/
https://www.ncbi.nlm.nih.gov/pubmed/26357657
http://dx.doi.org/10.1155/2015/652017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556869/
https://www.ncbi.nlm.nih.gov/pubmed/26357657
http://dx.doi.org/10.1155/2015/652017

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