Cargando…

BRCA1 185delAG Mutation Enhances Interleukin-1β Expression in Ovarian Surface Epithelial Cells

Familial history remains the strongest risk factor for developing ovarian cancer (OC) and is associated with germline BRCA1 mutations, such as the 185delAG founder mutation. We sought to determine whether normal human ovarian surface epithelial (OSE) cells expressing the BRCA1 185delAG mutant, BRAT,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Woolery, Kamisha T., Mohamed, Mai, Linger, Rebecca J., Dobrinski, Kimberly P., Roman, Jesse, Kruk, Patricia A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556869/ https://www.ncbi.nlm.nih.gov/pubmed/26357657 http://dx.doi.org/10.1155/2015/652017

Ejemplares similares

Ovarian Epithelial-Stromal Interactions: Role of Interleukins 1 and 6
por: Woolery, Kamisha T., et al.
Publicado: (2011)

Prevalence of the BRCA1 c.68_69delAG (BIC: 185delAG) mutation in women with breast cancer from north-central Poland and a review of the literature on other regions of the country
por: Hartwig, Martyna, et al.
Publicado: (2013)

Absence of 185delAG mutation of the BRCA1 gene and 6174delT mutation of the BRCA2 gene in Ashkenazi Jewish men with prostate cancer.
por: Lehrer, S., et al.
Publicado: (1998)

Prevalence of 185delAG and 5382insC mutations in BRCA1, and 6174delT in BRCA2 in women of Ashkenazi Jewish origin in southern Brazil
por: Dillenburg, Crisle Vignol, et al.
Publicado: (2012)

Origin and distribution of the BRCA2-8765delAG mutation in breast cancer
por: Palomba, Grazia, et al.
Publicado: (2007)

Strong founder effect for BRCA1 c.3629_3630delAG pathogenic variant in Chechen patients with breast or ovarian cancer
por: Sokolenko, Anna P., et al.
Publicado: (2022)

Urinary interleukin-1β levels among gynecological patients
por: Woolery, Kamisha T, et al.
Publicado: (2014)

BRCA1 c.68_69delAG (exon2), c.181T>G (exon5), c.798_799delTT and 943ins10 (exon11) mutations in Burkina Faso
por: Zoure, Abdou Azaque, et al.
Publicado: (2018)

BRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells
por: Johnson, Nicole C, et al.
Publicado: (2002)

Association of BRCA1 185 del AG with early age onset of breast cancer patients in selected cohort from Pakistani population
por: Durr-e-Samin,, et al.
Publicado: (2018)

c.753_754delAG, a novel CFTR mutation found in a Chinese patient with cystic fibrosis: A case report and review of the literature
por: Wang, Yu-Qing, et al.
Publicado: (2019)

Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil
por: Maistro, Simone, et al.
Publicado: (2016)

The BRCA Gene in Epithelial Ovarian Cancer
por: Sánchez-Lorenzo, Luisa, et al.
Publicado: (2022)

Na(1.85)Mg(1.85)In(1.15)(PO(4))(3) and Ag(1.69)Mg(1.69)In(1.31)(PO(4))(3) with alluaudite-type structures
por: Ould Saleck, Ahmed, et al.
Publicado: (2018)

BRCA1 as a Therapeutic Target in Sporadic Epithelial Ovarian Cancer
por: Clark-Knowles, Katherine V., et al.
Publicado: (2010)

BRCA1 expression, proliferative and apoptotic activities in ovarian epithelial inclusions
por: Wang, Yiying, et al.
Publicado: (2017)

Prevalence and clinical characterization of BRCA1 and BRCA2 mutations in Korean patients with epithelial ovarian cancer
por: Paik, E Sun, et al.
Publicado: (2021)

BRCA immunohistochemistry for screening of BRCA mutation in epithelial ovarian cancer patients
por: Manchana, Tarinee, et al.
Publicado: (2020)

BRCA1 Regulates Follistatin Function in Ovarian Cancer and Human Ovarian Surface Epithelial Cells
por: Karve, Tejaswita M., et al.
Publicado: (2012)

Reclassification of BRCA1 and BRCA2 variants found in ovarian epithelial, fallopian tube, and primary peritoneal cancers
por: Ha, Hyeong In, et al.
Publicado: (2020)

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants
por: Barnes, Daniel R., et al.
Publicado: (2020)

New paradigms for BRCA1/BRCA2 testing in women with ovarian cancer: results of the Genetic Testing in Epithelial Ovarian Cancer (GTEOC) study
por: Plaskocinska, Inga, et al.
Publicado: (2016)

The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer
por: McCoy, Marcia L, et al.
Publicado: (2003)

BRCA mutation in high grade epithelial ovarian cancers
por: Manchana, Tarinee, et al.
Publicado: (2019)

Reliability of Tumor Testing Compared to Germline Testing for Detecting BRCA1 and BRCA2 Mutations in Patients with Epithelial Ovarian Cancer
por: Bekos, Christine, et al.
Publicado: (2021)

The Impact of BRCA1- and BRCA2 Mutations on Ovarian Reserve Status
por: C.E, Drechsel Katja, et al.
Publicado: (2022)

BRCA1 promoter hypermethylation in sporadic epithelial ovarian carcinoma: Association with low expression of BRCA1, improved survival and co-expression of DNA methyltransferases
por: BAI, XUEFENG, et al.
Publicado: (2014)

Molecular analysis of the BRCA1 and BRCA2 genes in 32 breast and/or ovarian cancer Spanish families
por: Osorio, A, et al.
Publicado: (2000)

Germline and Somatic BRCA1/2 Mutations in 172 Chinese Women With Epithelial Ovarian Cancer
por: You, Yan, et al.
Publicado: (2020)

Similarities and differences in gene expression profiles of BRCA1 methylated and mutated epithelial ovarian cancers
por: Sahnane, Nora, et al.
Publicado: (2023)

BRCA1/2 testing rates in epithelial ovarian cancer: a focus on the untested patients
por: Lanjouw, Lieke, et al.
Publicado: (2023)

Transcriptome Patterns of BRCA1- and BRCA2- Mutated Breast and Ovarian Cancers
por: Arakelyan, Arsen, et al.
Publicado: (2021)

Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2
por: O’Mahony, Denise G., et al.
Publicado: (2023)

Induction of Ovarian Leiomyosarcomas in Mice by Conditional Inactivation of Brca1 and p53
por: Quinn, Bridget A., et al.
Publicado: (2009)

BRCA Mutations—The Achilles Heel of Breast, Ovarian and Other Epithelial Cancers
por: Loboda, Anna P., et al.
Publicado: (2023)

Prevalence of tumor BRCA1 and BRCA2 dysfunction in unselected patients with ovarian cancer
por: Kalachand, Roshni D., et al.
Publicado: (2020)

BRCA1 and BRCA2 mutations in ovarian cancer patients from Belarus: update
por: Savanevich, Alena, et al.
Publicado: (2021)

Hereditary Ovarian Carcinoma: Cancer Pathogenesis Looking beyond BRCA1 and BRCA2
por: Samuel, David, et al.
Publicado: (2022)

Landscape of germline BRCA1/BRCA2 variants in breast and ovarian cancer in Peru
por: Ferreyra, Yomali, et al.
Publicado: (2023)

Radioisotope yields from 1.85-GeV protons on Mo and 1.85- and 5.0-GeV protons on Te
por: Bardayan, D W, et al.
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_vft9bi4f6gjpr9hb14nf9r305f