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Inhibitory Effects of Cytosolic Ca(2+) Concentration by Ginsenoside Ro Are Dependent on Phosphorylation of IP(3)RI and Dephosphorylation of ERK in Human Platelets

Intracellular Ca(2+) ([Ca(2+)](i)) is platelet aggregation-inducing molecule and is involved in activation of aggregation associated molecules. This study was carried out to understand the Ca(2+)-antagonistic effect of ginsenoside Ro (G-Ro), an oleanane-type saponin in Panax ginseng. G-Ro, without a...

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Detalles Bibliográficos
Autores principales: Kwon, Hyuk-Woo, Shin, Jung-Hae, Lee, Dong-Ha, Park, Hwa-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556879/
https://www.ncbi.nlm.nih.gov/pubmed/26355658
http://dx.doi.org/10.1155/2015/764906