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Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy

Maximising the use of preclinical murine models of progressive kidney disease as test beds for therapies ideally requires kidney function to be measured repeatedly in a safe, minimally invasive manner. To date, most studies of murine nephropathy depend on unreliable markers of renal physiological fu...

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Detalles Bibliográficos
Autores principales: Scarfe, Lauren, Rak-Raszewska, Aleksandra, Geraci, Stefania, Darssan, Darsy, Sharkey, Jack, Huang, Jiaguo, Burton, Neal C., Mason, David, Ranjzad, Parisa, Kenny, Simon, Gretz, Norbert, Lévy, Raphaël, Kevin Park, B., García-Fiñana, Marta, Woolf, Adrian S., Murray, Patricia, Wilm, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556979/
https://www.ncbi.nlm.nih.gov/pubmed/26329825
http://dx.doi.org/10.1038/srep13601