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High-Level Expression, Purification and Large-Scale Production of l-Methionine γ-Lyase from Idiomarina as a Novel Anti-Leukemic Drug

l-Methionine γ-lyase (MGL), a pyridoxal 5′-phosphate-dependent enzyme, possesses anti-tumor activity. However, the low activity of MGL blocks the anti-tumor effect. This study describes an efficient production process for the recombinant MGL (rMGL) from Idiomarina constructed using the overexpressio...

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Detalles Bibliográficos
Autores principales:	Huang, Kui-Ying, Hu, Hai-Yan, Tang, Yan-Lai, Xia, Feng-Geng, Luo, Xue-Qun, Liu, Jian-Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557031/ https://www.ncbi.nlm.nih.gov/pubmed/26308011 http://dx.doi.org/10.3390/md13085492

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