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Benchmarking the stability of human detergent-solubilised voltage-gated sodium channels for structural studies using eel as a reference
With the ultimate goal of detailed structural analysis of mammalian and particularly human voltage-gated sodium channels (VGSCs), we have investigated the relative stability of human and rat VGSCs and compared them with electric eel VGSC. We found that NaV1.3 from rat was the most stable after deter...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Pub. Co
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557063/ https://www.ncbi.nlm.nih.gov/pubmed/25838126 http://dx.doi.org/10.1016/j.bbamem.2015.03.021 |