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Benchmarking the stability of human detergent-solubilised voltage-gated sodium channels for structural studies using eel as a reference

With the ultimate goal of detailed structural analysis of mammalian and particularly human voltage-gated sodium channels (VGSCs), we have investigated the relative stability of human and rat VGSCs and compared them with electric eel VGSC. We found that NaV1.3 from rat was the most stable after deter...

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Detalles Bibliográficos
Autores principales: Slowik, Daria, Henderson, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557063/
https://www.ncbi.nlm.nih.gov/pubmed/25838126
http://dx.doi.org/10.1016/j.bbamem.2015.03.021