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Phosphoproteomic profiling of tumor tissues identifies HSP27 Ser82 phosphorylation as a robust marker of early ischemia

Delays between tissue collection and tissue fixation result in ischemia and ischemia-associated changes in protein phosphorylation levels, which can misguide the examination of signaling pathway status. To identify a biomarker that serves as a reliable indicator of ischemic changes that tumor tissue...

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Detalles Bibliográficos
Autores principales: Zahari, Muhammad Saddiq, Wu, Xinyan, Pinto, Sneha M., Nirujogi, Raja Sekhar, Kim, Min-Sik, Fetics, Barry, Philip, Mathew, Barnes, Sheri R., Godfrey, Beverly, Gabrielson, Edward, Nevo, Erez, Pandey, Akhilesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557083/
https://www.ncbi.nlm.nih.gov/pubmed/26329039
http://dx.doi.org/10.1038/srep13660