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Misframed ubiquitin and impaired protein quality control: an early event in Alzheimer’s disease
Amyloid β (Aβ) plaque formation is a prominent cellular hallmark of Alzheimer’s disease (AD). To date, immunization trials in AD patients have not been effective in terms of curing or ameliorating dementia. In addition, γ-secretase inhibitor strategies await clinical improvements in AD. These approa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557111/ https://www.ncbi.nlm.nih.gov/pubmed/26388726 http://dx.doi.org/10.3389/fnmol.2015.00047 |