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Misframed ubiquitin and impaired protein quality control: an early event in Alzheimer’s disease

Amyloid β (Aβ) plaque formation is a prominent cellular hallmark of Alzheimer’s disease (AD). To date, immunization trials in AD patients have not been effective in terms of curing or ameliorating dementia. In addition, γ-secretase inhibitor strategies await clinical improvements in AD. These approa...

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Detalles Bibliográficos
Autores principales:	Gentier, Romina J., van Leeuwen, Fred W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557111/ https://www.ncbi.nlm.nih.gov/pubmed/26388726 http://dx.doi.org/10.3389/fnmol.2015.00047

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