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Slow-growing cells within isogenic populations have increased RNA polymerase error rates and DNA damage
Isogenic cells show a large degree of variability in growth rate, even when cultured in the same environment. Such cell-to-cell variability in growth can alter sensitivity to antibiotics, chemotherapy and environmental stress. To characterize transcriptional differences associated with this variabil...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557116/ https://www.ncbi.nlm.nih.gov/pubmed/26268986 http://dx.doi.org/10.1038/ncomms8972 |