Slow-growing cells within isogenic populations have increased RNA polymerase error rates and DNA damage

Isogenic cells show a large degree of variability in growth rate, even when cultured in the same environment. Such cell-to-cell variability in growth can alter sensitivity to antibiotics, chemotherapy and environmental stress. To characterize transcriptional differences associated with this variabil...

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Detalles Bibliográficos
Autores principales: van Dijk, David, Dhar, Riddhiman, Missarova, Alsu M., Espinar, Lorena, Blevins, William R., Lehner, Ben, Carey, Lucas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557116/
https://www.ncbi.nlm.nih.gov/pubmed/26268986
http://dx.doi.org/10.1038/ncomms8972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557116/
https://www.ncbi.nlm.nih.gov/pubmed/26268986
http://dx.doi.org/10.1038/ncomms8972

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