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Micro-concentration Lipopolysaccharide as a Novel Stimulator of Megakaryocytopoiesis that Synergizes with IL-6 for Platelet Production

Lipopolysaccharide (LPS) induces platelet activation and enhances platelet sensitivity to aggregation, which might alter platelet counts. We found that serial doses of micro-concentration LPS significantly increased the platelet count in mice treated with kanamycin, along with increased expression o...

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Detalles Bibliográficos
Autores principales: Wu, Di, Xie, Jun, Wang, Xuejun, Zou, Bingcheng, Yu, Yin, Jing, Tao, Zhang, Songmei, Zhang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557119/
https://www.ncbi.nlm.nih.gov/pubmed/26330186
http://dx.doi.org/10.1038/srep13748