Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology

Alzheimer's disease (AD) is a neurodegenerative disorder in which chronic neuroinflammation contributes to disease escalation. Nevertheless, while immunosuppressive drugs have repeatedly failed in treating this disease, recruitment of myeloid cells to the CNS was shown to play a reparative role...

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Detalles Bibliográficos
Autores principales: Baruch, Kuti, Rosenzweig, Neta, Kertser, Alexander, Deczkowska, Aleksandra, Sharif, Alaa Mohammad, Spinrad, Amit, Tsitsou-Kampeli, Afroditi, Sarel, Ayelet, Cahalon, Liora, Schwartz, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557123/
https://www.ncbi.nlm.nih.gov/pubmed/26284939
http://dx.doi.org/10.1038/ncomms8967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557123/
https://www.ncbi.nlm.nih.gov/pubmed/26284939
http://dx.doi.org/10.1038/ncomms8967

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