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Multivalency governs HP1α association dynamics with the silent chromatin state

Multivalent interactions between effector proteins and histone post-translational modifications are an elementary mechanism of dynamic chromatin signalling. Here we elucidate the mechanism how heterochromatin protein 1α (HP1α), a multivalent effector, is efficiently recruited to the silent chromatin...

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Detalles Bibliográficos
Autores principales: Kilic, Sinan, Bachmann, Andreas L., Bryan, Louise C., Fierz, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557296/
https://www.ncbi.nlm.nih.gov/pubmed/26084584
http://dx.doi.org/10.1038/ncomms8313