CRL4–DCAF1 ubiquitin E3 ligase directs protein phosphatase 2A degradation to control oocyte meiotic maturation

Oocyte meiosis is a specialized cell cycle that gives rise to fertilizable haploid gametes and is precisely controlled in various dimensions. We recently found that E3 ubiquitin ligase CRL4 is required for female fertility by regulating DNA hydroxymethylation to maintain oocyte survival and to promo...

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Detalles Bibliográficos
Autores principales: Yu, Chao, Ji, Shu-Yan, Sha, Qian-Qian, Sun, Qing-Yuan, Fan, Heng-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557334/
https://www.ncbi.nlm.nih.gov/pubmed/26281983
http://dx.doi.org/10.1038/ncomms9017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557334/
https://www.ncbi.nlm.nih.gov/pubmed/26281983
http://dx.doi.org/10.1038/ncomms9017

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