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Identification of Aberrant Chromosomal Regions in Human Breast Cancer Using Gene Expression Data and Related Gene Information

BACKGROUND: Chromosomal instability is a hallmark of cancer. Chromosomal imbalances, like amplifications and deletions, influence the transcriptional activity of genes. These imbalances affect not only the expression of genes in the aberrant chromosomal regions, but also that of related genes, and m...

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Detalles Bibliográficos
Autores principales: Wang, Hong-Jiu, Zhou, Meng, Jia, Li, Sun, Jie, Shi, Hong-Bo, Liu, Shu-Lin, Wang, Zhen-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557392/
https://www.ncbi.nlm.nih.gov/pubmed/26319982
http://dx.doi.org/10.12659/MSM.894887