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CD4(+)CD25(High) Treg cells in HIV/HTLV Co-infected patients with neuropathy: high expression of Alpha4 integrin and lower expression of Foxp3 transcription factor

BACKGROUND: Regulatory CD4 T cells (Tregs) are critical in maintaining the homeostasis of the immune system. Quantitative or phenotypic alterations and functional impairment of Tregs have been associated with the development of pathologies including those of the central nervous system. Individuals w...

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Detalles Bibliográficos
Autores principales: Matavele Chissumba, Raquel, Silva-Barbosa, Suse Dayse, Augusto, Ângelo, Maueia, Cremildo, Mabunda, Nédio, Gudo, Eduardo Samo, Bhatt, Nilesh, Jani, Ilesh, Savino, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557637/
https://www.ncbi.nlm.nih.gov/pubmed/26329520
http://dx.doi.org/10.1186/s12865-015-0116-x