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CD4(+)CD25(High) Treg cells in HIV/HTLV Co-infected patients with neuropathy: high expression of Alpha4 integrin and lower expression of Foxp3 transcription factor
BACKGROUND: Regulatory CD4 T cells (Tregs) are critical in maintaining the homeostasis of the immune system. Quantitative or phenotypic alterations and functional impairment of Tregs have been associated with the development of pathologies including those of the central nervous system. Individuals w...
Autores principales: | Matavele Chissumba, Raquel, Silva-Barbosa, Suse Dayse, Augusto, Ângelo, Maueia, Cremildo, Mabunda, Nédio, Gudo, Eduardo Samo, Bhatt, Nilesh, Jani, Ilesh, Savino, Wilson |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557637/ https://www.ncbi.nlm.nih.gov/pubmed/26329520 http://dx.doi.org/10.1186/s12865-015-0116-x |
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