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Polymorphism in microRNA-binding site in HNF1B influences the susceptibility of type 2 diabetes mellitus: a population based case–control study

BACKGROUND: Recent genome-wide association studies (GWAS) have identified many SNPs associated with type 2 diabetes mellitus (T2DM). However, the functional roles for most of the SNPs have not been elucidated. MicroRNAs (miRNAs) are key regulators of gene expression involved in the development and p...

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Detalles Bibliográficos
Autores principales: Goda, Naoki, Murase, Haruna, Kasezawa, Nobuhiko, Goda, Toshinao, Yamakawa-Kobayashi, Kimiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557749/
https://www.ncbi.nlm.nih.gov/pubmed/26329304
http://dx.doi.org/10.1186/s12881-015-0219-5