Cargando…

Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution

Although the locations of promoters and enhancers have been identified in several cell types, we still have limited information on their connectivity. We developed HiCap, which combines a 4-cutter restriction enzyme Hi-C with sequence capture of promoter regions. Applying the method to mouse embryon...

Descripción completa

Detalles Bibliográficos
Autores principales: Sahlén, Pelin, Abdullayev, Ilgar, Ramsköld, Daniel, Matskova, Liudmila, Rilakovic, Nemanja, Lötstedt, Britta, Albert, Thomas J., Lundeberg, Joakim, Sandberg, Rickard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557751/
https://www.ncbi.nlm.nih.gov/pubmed/26313521
http://dx.doi.org/10.1186/s13059-015-0727-9