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Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution
Although the locations of promoters and enhancers have been identified in several cell types, we still have limited information on their connectivity. We developed HiCap, which combines a 4-cutter restriction enzyme Hi-C with sequence capture of promoter regions. Applying the method to mouse embryon...
Autores principales: | Sahlén, Pelin, Abdullayev, Ilgar, Ramsköld, Daniel, Matskova, Liudmila, Rilakovic, Nemanja, Lötstedt, Britta, Albert, Thomas J., Lundeberg, Joakim, Sandberg, Rickard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557751/ https://www.ncbi.nlm.nih.gov/pubmed/26313521 http://dx.doi.org/10.1186/s13059-015-0727-9 |
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