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Reactive oxygen species scavenger N-acetyl cysteine reduces methamphetamine-induced hyperthermia without affecting motor activity in mice

Hyperthermia is a potentially lethal side effect of Methamphetamine (Meth) abuse, which involves the participation of peripheral thermogenic sites such as the Brown Adipose Tissue (BAT). In a previous study we found that the anti-oxidant N-acetyl cysteine (NAC) can prevent the high increase in tempe...

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Detalles Bibliográficos
Autores principales: Sanchez-Alavez, Manuel, Bortell, Nikki, Galmozzi, Andrea, Conti, Bruno, Marcondes, Maria Cecilia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557806/
https://www.ncbi.nlm.nih.gov/pubmed/26346736
http://dx.doi.org/10.4161/23328940.2014.984556