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Exploring the cellular basis of human disease through a large-scale mapping of deleterious genes to cell types
BACKGROUND: Each cell type found within the human body performs a diverse and unique set of functions, the disruption of which can lead to disease. However, there currently exists no systematic mapping between cell types and the diseases they can cause. METHODS: In this study, we integrate protein–p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557825/ https://www.ncbi.nlm.nih.gov/pubmed/26330083 http://dx.doi.org/10.1186/s13073-015-0212-9 |